A clinical treatment study to examine aphasia recovery after stroke and how people respond to treatment with a speech-language pathologist in-person versus online. Individuals who have experienced a left hemisphere stroke and continue to experience communication difficulties may be eligible. A total of 6 weeks of daily treatment (45 minutes) is received either remotely or in-clinic. All participants will receive 3 weeks of phonological (focus on sounds) and semantic (focus on word meaning) treatments. We can assist with lodging and transportation as needed.

We are doing a study to help people who have difficulty communicating after a stroke. We want to compare how people improve with speech therapy: In person (at a clinic), or Online (at home by computer). You may join if: You had a stroke on the left side of your brain, and You still have trouble talking or understanding words. You are between the ages of 21-80 The study gives 6 weeks of speech therapy. Each session is 45 minutes, Monday to Friday. Everyone will get: 3 weeks of sound-based therapy (phonology), and 3 weeks of word-meaning therapy (semantics). We can help with lodging during your stay in Columbia, SC and transportation if needed.

Inclusion: -Between 21-80 years old -Left brain stroke at least 12 months ago -English as your primary language for at least 20 years -Able to provide informed written or verbal consent -Able to have an MRI scan -Auditory comprehension and verbal expression skills to participate in specific therapy tasks

Sara Sayers

ssayers@mailbox.sc.edu

Stroke

Treatment

Semantic and Phonological Treatment

4 days of baseline testing, 30 treatment sessions, 1 day of testing/MRI after round 1 of treatment and after round 2 of treatment, and at 6 months post treatment completion, total spanning 39 weeks.

March 31, 2026

Reimburse mileage one-way. We will book and pay for lodging.

105675