The purpose of this study is to evaluate how changing conditions of speech-language treatment (namely, amount of repetition and distribution of practice schedule) affects the language outcome of participants with aphasia following a stroke. Using a computer-based speech and language therapy program, participants will practice conversational scripts that are either short or long. Participants will practice for either 2 weeks (5 days a week) or for 5 weeks (2 days a week).

• Conversation practice on the computer with a “virtual therapist” • We will loan you all equipment needed for the study • Participation in the study lasts either 11 weeks or 14 weeks • You will receive 10 treatment sessions. Treatment lasts either 2 weeks or 5 weeks: o 2-week schedule: 1 hour/day, 5 days/week o 5-week schedule: 1 hour/day, 2 days/week • All visits online (Zoom) OR in-person with Shirley Ryan AbilityLab research staff: o Evaluations (4 times, 1-2 days each) o Training (1-2 days)

Inclusion Criteria: -Persons age 18+ with a diagnosis of aphasia -Left brain stroke -At least 6 months post stroke -Completed at least eighth grade education -Premorbidly literate in English -Adequate vision and hearing to participate in study protocols -Not receiving speech-language therapy at the time of study Exclusion Criteria: -Any other neurological condition (other than cerebral vascular disease) that could potentially affect cognition or speech, such as Parkinson's Disease, Alzheimer's Dementia, traumatic brain injury -Any significant psychiatric history prior to the stroke, such as severe major depression or psychotic disorder requiring hospitalization; subjects with mood disorders who are currently stable on treatment will be considered -Active substance abuse

Leora Cherney

lcherney@sralab.org

Stroke

Treatment

Script Training

Participation in the study lasts either 11 weeks (2-week schedule) or 14 weeks (5-week schedule). All participants receive 10 treatment sessions.

June 30, 2024

Participants will be compensated for their participation in the study.

209618